延續1月份老化認知神經研習課程,於02/27敬邀德國 TU Dresden Section of Lifespan Developmental Neuroscience, Germany, Chair of Lifespan Developmental Neuroscience 李淑珍教授前來分享老化相關議題的研究,並於會後提供簡單茶水。(請自備環保杯)
題目:Implications of Aging Neuronal Gain Control on Adaptive Cognition and Decision Making in Old Age
講者:李淑珍 教授 PROF. SHU-CHEN LI, Ph.D.
(Chair of Lifespan Developmental Neuroscience TU Dresden Section of Lifespan Developmental Neuroscience,Germany )
講者簡歷:http://ppt.cc/XhW9
演講摘要:
The efficacy of various transmitter systems declines with advancing age. Of particular interest, various pre-synaptic and post-synaptic components of the dopaminergic system change across the human lifespan; impairments in these components play important roles in cognitive deficits commonly observed in the elderly.
Here,we review evidence from recent multimodal neuroimaging, pharmacological and genetic studies that have provided new insights for the associations among dopamine functions, aging, functional brain activations and behavioral performance across key cognitive functions, ranging from working memory and episodic memory to goal-directed learning and decision making. Specifically, we discuss these empirical findings in the context of an established neurocomputational theory of aging neuronal gain control. We also highlight gaps in the current understanding of dopamine neuromodulation and aging brain functions and suggest avenues for future research.